phospho stat3 (Cell Signaling Technology Inc)
Cell Signaling Technology Inc is a verified supplier 
Cell Signaling Technology Inc manufactures this product 
98
Structured Review
Cell Signaling Technology Inc
phospho stat3
Phospho Stat3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 98/100, based on 6135 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+phospho+stat3+antibody/Phospho-Stat3+(Tyr705)+XP+Rabbit+mAb/pmc13640141-140-39-43
Average 98 stars, based on 6135 article reviews
Phospho Stat3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 98/100, based on 6135 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+phospho+stat3+antibody/Phospho-Stat3+(Tyr705)+XP+Rabbit+mAb/pmc13640141-140-39-43
Average 98 stars, based on 6135 article reviews
phospho stat3 - by Bioz Stars,
2026-10
98/100 stars
Images
1) Product Images from "Kaempferol ameliorates gestational diabetes mellitus by regulating STAT3-associated AIM2 inflammasome activation and ferroptotic injury in trophoblasts"
Article Title: Kaempferol ameliorates gestational diabetes mellitus by regulating STAT3-associated AIM2 inflammasome activation and ferroptotic injury in trophoblasts
Journal: Frontiers in Physiology
doi: 10.3389/fphys.2026.1857741
Figure Legend Snippet: KPF ameliorates placental pathological changes and oxidative stress in GDM rats. (A) HE staining was performed to evaluate pathological alterations in placental tissues. Magnification: 100×; scale bar: 200 μm. (B) PAS staining was performed to assess glycogen distribution and deposition in placental tissues. Magnification: 100×; scale bar: 200 μm. (C, D) DHE staining was performed to evaluate ROS accumulation in placental tissues. Magnification: 200×; scale bar: 20 μm. (E–I) Western blot analysis was performed to determine the protein expression levels of AIM2, p-STAT3, GPX4, and SLC7A11 in placental tissues. N = 3, * P < 0.05, ** P < 0.01, *** P < 0.001.
Techniques Used: H&E Stain, Staining, Western Blot, Analysis, Expressing
Figure Legend Snippet: KPF modulates trophoblast inflammatory responses and ferroptosis-related alterations through STAT3-associated signaling regulation. (A) Molecular docking analysis showing the potential interaction between KPF and STAT3 protein. (B, C) RT-qPCR analysis of STAT3 mRNA expression and transfection efficiency in HTR-8/SVneo cells. (D) CCK-8 assay was used to evaluate cell viability. (E, F) ELISA quantification of inflammatory cytokines IL-18 and TNF-α in cell supernatants. (G–L) Western blot analysis of AIM2, IL-1β, pro-IL-1β, GPX4, SLC7A11, cleaved caspase-1, and pro-caspase-1 protein expression in cells subjected to various treatments. (M–P) Western blot analysis of STAT3-associated changes in STAT3, GPX4, and SLC7A11 protein expression in cells subjected to various treatments. N = 3, not significant, * P < 0.05, ** P < 0.01, *** P < 0.001.
Techniques Used: Docking Assay, Analysis, Quantitative RT-PCR, Expressing, Transfection, CCK-8 Assay, Enzyme-linked Immunosorbent Assay, Western Blot
Figure Legend Snippet: STAT3-associated changes in STAT1/IRF1 signaling and AIM2 expression in HG-stimulated trophoblast cells. (A, B) RT-qPCR was performed to assess STAT3 knockdown efficiency and AIM2 mRNA expression changes in HTR-8/SVneo cells subjected to different treatments. (C–F) Western blot analysis was performed to evaluate the expression levels of p-STAT1, STAT1, IRF1, and AIM2 proteins under different experimental conditions. N = 3, not significant, ** P <0.01, *** P <0.001.
Techniques Used: Expressing, Quantitative RT-PCR, Knockdown, Western Blot, Analysis
Related Articles
other:Article Title: Co-targeting CDK4/6 enhances anti-cancer activity and alleviates immune-related adverse events of anti-PD-1 antibody for breast cancer Article Snippet: SDS Page:Article Title: Peptides inhibiting gamma-c-cytokine activity and methods of use Article Snippet: .. The extracted cytoplasmic proteins were resolved using a standard SDS-PAGE (Sodium Dodecyl-Sulfate PolyAcrylamide Gel Electrophoresis) and the phosphorylation status was confirmed by an anti-phospho-STAT5 antibody (Cell Signaling Technology, Catalog #9354, Danvers MA) or an Article Title: STAT3 regulates NK and NKT cell differentiation through C-X3-C motif chemokine receptor 1 (CX3CR1) in hyper-IgE syndrome Article Snippet: .. Proteins were separated using 8% SDS-PAGE and then incubated with anti-STAT3 antibody (Cat#A22264, CST) and Polyacrylamide Gel Electrophoresis:Article Title: Peptides inhibiting gamma-c-cytokine activity and methods of use Article Snippet: .. The extracted cytoplasmic proteins were resolved using a standard SDS-PAGE (Sodium Dodecyl-Sulfate PolyAcrylamide Gel Electrophoresis) and the phosphorylation status was confirmed by an anti-phospho-STAT5 antibody (Cell Signaling Technology, Catalog #9354, Danvers MA) or an Phospho-proteomics:Article Title: Peptides inhibiting gamma-c-cytokine activity and methods of use Article Snippet: .. The extracted cytoplasmic proteins were resolved using a standard SDS-PAGE (Sodium Dodecyl-Sulfate PolyAcrylamide Gel Electrophoresis) and the phosphorylation status was confirmed by an anti-phospho-STAT5 antibody (Cell Signaling Technology, Catalog #9354, Danvers MA) or an Article Title: Apigenin regulates CCR5/JAK1/STAT1/MMPs signaling to alleviate secondary brain injury after intracerebral hemorrhage and its enhanced delivery via targeted nanoparticles Article Snippet: Different concentrations of apigenin (10 μM and 20 μM; Cat# A800500, Macklin, China) were added to the reaction system, which was maintained at 30 °C for 30 min. .. Reactions were terminated by adding 1× Laemmli buffer (Cat# 1610747, Bio-Rad, USA) and boiling at 95 °C for 5 min. Western blotting was performed using an Article Title: Apigenin regulates CCR5/JAK1/STAT1/MMPs signaling to alleviate secondary brain injury after intracerebral hemorrhage and its enhanced delivery via targeted nanoparticles. Article Snippet: Different concentrations of apigenin (10 μM and 20 μM; Cat# A800500, Macklin, China) were added to the reaction system, which was maintained at 30 °C for 30 min. .. Reactions were terminated by adding 1× Laemmli buffer (Cat# 1610747, Bio-Rad, USA) and boiling at 95 °C for 5 min. Western blotting was performed using an Western Blot:Article Title: Peptides inhibiting gamma-c-cytokine activity and methods of use Article Snippet: .. The extracted cytoplasmic proteins were resolved using a standard SDS-PAGE (Sodium Dodecyl-Sulfate PolyAcrylamide Gel Electrophoresis) and the phosphorylation status was confirmed by an anti-phospho-STAT5 antibody (Cell Signaling Technology, Catalog #9354, Danvers MA) or an Article Title: Apigenin regulates CCR5/JAK1/STAT1/MMPs signaling to alleviate secondary brain injury after intracerebral hemorrhage and its enhanced delivery via targeted nanoparticles Article Snippet: Different concentrations of apigenin (10 μM and 20 μM; Cat# A800500, Macklin, China) were added to the reaction system, which was maintained at 30 °C for 30 min. .. Reactions were terminated by adding 1× Laemmli buffer (Cat# 1610747, Bio-Rad, USA) and boiling at 95 °C for 5 min. Western blotting was performed using an Article Title: Apigenin regulates CCR5/JAK1/STAT1/MMPs signaling to alleviate secondary brain injury after intracerebral hemorrhage and its enhanced delivery via targeted nanoparticles. Article Snippet: Different concentrations of apigenin (10 μM and 20 μM; Cat# A800500, Macklin, China) were added to the reaction system, which was maintained at 30 °C for 30 min. .. Reactions were terminated by adding 1× Laemmli buffer (Cat# 1610747, Bio-Rad, USA) and boiling at 95 °C for 5 min. Western blotting was performed using an Incubation:Article Title: Investigation of the pharmacological mechanisms of Denglao Qingguan decoction in inhibiting viral pneumonia through network pharmacology and in vitro laboratory validation Article Snippet: .. The primary antibodies including anti-Stat3 antibody (Stat3, cat# 4904S, CST, United States), Article Title: STAT3 regulates NK and NKT cell differentiation through C-X3-C motif chemokine receptor 1 (CX3CR1) in hyper-IgE syndrome Article Snippet: .. Proteins were separated using 8% SDS-PAGE and then incubated with anti-STAT3 antibody (Cat#A22264, CST) and |
